The Importance of Building Muscle and Strength on Metabolic Health

Mar 20, 2026

To make muscle and strength a true health strategy you need repeatable metrics: compound‑lift strength and clinical strength tests and run an annual whole‑body DXA scan to track lean and fat mass over years. Lower strength is consistently associated with worse cognitive outcomes, and nutritional and exercise‑centric multidomain trials support cognition-preserving strategies. (PMID: 25771249; PMC: PMC7890203).

You can build muscle on a lower carb diet if the training and protein are right. A low‑carb or ketogenic diet does not inherently prevent hypertrophy, which is a question that comes up frequently. What builds muscle is the same on any diet: a mechanical stimulus (progressive training), sufficient amino acids (protein), and enough energy to recover and adapt. In resistance‑trained men, an isocaloric, isonitrogenous randomized trial comparing a ketogenic diet with a Western diet found lean body mass increased in both groups, and strength/power changes were broadly comparable during the training period. (PMID: 28399015). Across multiple studies, meta‑analytic evidence supports the practical conclusion that resistance‑training athletes can maintain and often increase fat‑free mass on ketogenic diets—especially when calories aren’t inadvertently too low and protein is sufficient. (PMID: 33624538; PMC: PMC9564904). A key nuance clinicians should communicate: body composition readouts can shift due to glycogen and water changes when carbohydrate intake changes. That doesn’t mean “muscle disappeared”—but it can influence short‑term DXA/FFM readings and how patients interpret early results. Longitudinal tracking (especially with standardized testing conditions) is the antidote. (PMC: PMC5659281)…

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Dominic D'AgostinoTampa, FL, US

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